What you're describing is technically regular link aggregation, not multi-chassis link aggregation.
MC-LAG is a LAG between a given switch (or cluster) and multiple other separate (i.e. un-clustered) switch chassis. Bear in mind that switches in a VC collectively behave as a single chassis, so building a LAG involving ports on separate physical switches in the same VC is done exactly the same way as building a regular LAG (add your aggregate interface, add the physical interfaces to the aggregate interface, configure LACP etc).
So yes, you can easily build a LAG between an EX2200 VC and an EX4300 VC, even split across physical switches. Just think of each VC as one big switch.